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Breaking Down the 2017 IFPMA Report: Life Expectancy

Breaking Down the 2017 IFPMA Report: Life Expectancy
In the age of advanced medical technology and global health awareness, human longevity is undeniable. Past life-threatening diseases and infections, such as hepatitis A and B, can now be prevented with a vaccine administered through a single shot. Through medical research and development (R&D) programs and projects, human life expectancy is expected to increase exponentially by 2030.

Many organizations exist toward the goal of extending human life expectancy. One such organization, the International Federation of Pharmaceutical Manufacturers & Associations (IFPMA) represents research-based biopharmaceutical companies and associations worldwide. IFPMA advocates for practices and policies that promote the access and discovery of life-saving medicines and vaccines. Through its two million employees at member companies and associations, IFPMA can successfully research, develop, and provide reliable statistical figures that help improve the lives of patients across the globe.

Here are 10 key facts from IFPMA’s 2017 Facts and Figures report:

  1. It takes between 10 and 15 years to successfully develop a medicine or vaccine.
  2. The research-based pharmaceutical industry presently spends over $149.8 billion on R&D annually.
  3. For every $1 spent on new medication for hypertension in the U.S., $10.11 is saved in medical spending.
  4. In 2015, 56 new pharmaceuticals became publicly available and more that 7,000 compounds are currently in development stages.
  5. The global pharmaceutical market will reach approximately USD $1.4 billion by 2020.
  6. The pharmaceutical industry’s private sector accounts for nearly all medicine and vaccines produced on the market.
  7. In 2014, over 401 pharmaceuticals were in various stages of development for diabetes and 208 drugs were in development for HIV/AIDS.
  8. IFPMA members currently have 119 R&D projects in the works for neglected tropical diseases.
  9. In 2014, the pharmaceutical industry was the third-largest contributor of neglected diseases research, investing over $534 million.
  10. The cost of developing a successful medication can exceed over $2.6 billion in R&D.

Research done by organizations like the IFPMA is consistently increasing human life expectancy. According to a study led by scientists from Imperial College London, the average life expectancy is expected to increase by 2030. The study was published in The Lancet and focuses on future life expectancy in 35 industrialized countries. It estimates life expectancy to increase by 65% for women and 85% for men in all 35 countries. The highest life expectancy was projected for South Korean women, with a 90% probability that nearly all women will survive to at least 86.7 years. Following South Korea, the highest projected female life expectancies are those in France, Spain and Japan. Of the 35 countries studied, the United States, Sweden, Greece and Serbia have some of the lowest predicted life expectancy projections for both men and women.

– Madison O’Connell

Photo: Flickr

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Cardiovascular Dominating Top Diseases in Latvia


The country of Latvia in Eastern Europe borders the Baltic Sea and Russia. The population of Latvia is just fewer than two million people, which is very small relative to most countries around the world. The life expectancy in Latvia is 74 years, which is above the global average of 71 years. The annual mortality rate is 754 per 100,000. Though it is small, the top diseases in Latvia mirror global trends.

When traveling to Latvia, it is recommended by the CDC to have all routine vaccinations up to date, as well as hepatitis A. There is the possibility of contaminated food and water in Latvia.

The top two diseases in Latvia are both cardiac-related, much like most of the world. The heart diseases are the only two on the list of the top diseases in Latvia that have stayed in their spot for the last 20 years. The numbers have been decreasing for both ischemic heart disease and stroke. In third place, cardiomyopathy is also heart-related and has been rising since last counted when it was in the ninth position.

An interesting development in Latvia over the last 20 years has been the rise of HIV/AIDS. It was not near the top in 1990 in position 83, but it has jumped to the sixth since then. This has encouraged a discussion of prevention and education efforts. Educating the public on the dangers and how to be safe can prevent cases and resulting fatalities.

The risk factors of many of the top diseases in Latvia include dietary choices, high blood pressure, smoking and alcohol use and physical inactivity.

– Brendin Axtman

Photo: Flickr

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Major Diseases in Burkina Faso: Improvements Left to be Made

Top Diseases in Burkina Faso
The major diseases in Burkina Faso are also some of the largest killers in the world. They are incredibly dangerous, common throughout the country, and may be separated into categories as follows: food or waterborne diseases; vector-borne diseases; water contact diseases; aerosolized dust or soil contact diseases; respiratory disease and animal contact diseases. Below are the most common diseases in Burkina Faso.

Hepatitis A
This is a form of viral hepatitis. It is transmitted by food and causes jaundice and fever. Most who die from it are children aged one to four. Although the death rate from hepatitis A is Burkina Faso is lower than any other country in Western sub-Saharan Africa, it is their most dangerous food and waterborne disease.

Hepatitis E
The deadliness of this disease in Burkina Faso is most common at age 80. At this age, hepatitis E kills 4.3 out of 100,000 people. The virus targets the liver and is most commonly transmitted through the fecal-oral route.

Typhoid Fever
This is another of many diseases in Burkina Faso commonly spread through fecal-oral routes. Those infected experience high fevers and, if left untreated, mortality rates can reach 20 percent of the infected population. The annual mortality rate for typhoid fever in Burkina Faso has decreased 5 percent since 1990. It is like hepatitis A in that it mostly kills young children aged one to four.

Malaria
Malaria affects more people in Burkina Faso than in other countries of Western sub-Saharan Africa, although the mortality rate dropped 26 percent between 1990 and 2013. That decline is significant, but the death rate from Malaria decreased 49 percent in Sierra Leone and 51 percent in Gambia over the same period.

Dengue Fever
This disease is commonly spread through mosquitoes. Dengue fever is less common than it used to be, with a 52 percent decrease since 1990. It will occasionally cause shock and hemorrhage, leading to death in 5 percent of cases. While one of the less common diseases in Burkina Faso, it is still prevalent.

This is only the beginning of the list for diseases in Burkina Faso. While the country is fighting for better and stronger health care and prevention systems for these diseases, its citizens continue to die of entirely preventable causes. Burkina Faso is on its way to saving a lot of lives with their improvements in health care system, and help from countries like the United States can only help them from here.

– Rilee Pickle

Photo: Flickr

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10 Facts About H1N1

H1N1 Facts
The H1N1 virus, or “swine flu” as it’s commonly known, was a strain of influenza that became pandemic in 2009. In the subsequent years, the virus was one of the most prevalent concerns of the worldwide medical community. Though the virus has not been as prominent in recent years, it can still infect people and have drastic effects in some regions of the world.

Here are 10 facts about H1N1 influenza:

  1. H1N1 is commonly referred to as the “swine flu” due to its similarities with the flu virus that affects pigs in North America. Further study has shown that it is different than the other virus and carries two genes that normally occur in European and Asian pigs, birds and people.
  2. The virus spreads the same way as the regular seasonal flu virus. It is contagious and can be contracted through coughing, sneezing or even talking to someone carrying it. It can also be contracted through mouth or nose contact with something contaminated.
  3. The H1N1 influenza virus causes moderate to severe respiratory infections. Symptoms include fever, sore throat, cough, headache, chills and fatigue. Severe cases include bacterial pneumonia bronchitis, sinus infections and an increase in underlying conditions.
  4. H1N1 is most severe in infants, young children, the elderly and individuals with pre-existing chronic diseases. Mortality rates in people less than 65 are significantly higher than those associated with the common flu.
  5. People infected with H1N1 become contagious generally one day before showing symptoms and can continue to spread the virus for five to seven days after. Those with weaker immune systems, such as children, are generally contagious for longer.
  6. H1N1 can also affect various farm animals, including pigs and turkeys. Domestic animals such as dogs, cats and ferrets are also susceptible to the virus due to close contact with humans.
  7. It is estimated that more than half of the deaths caused by the H1N1 were in the Southeast Asian and African regions. This could be due in part to the quality of healthcare and limited availability of vaccines and medications.
  8. An estimated 105,700-395,600 people died due to respiratory complications attributed to H1N1 influenza during the first 12 months of the virus’s outbreak. This constitutes 0.001-0.007 percent of the world’s population.
  9. The virus was given pandemic status in 2009 after the disease spread rapidly throughout the U.S. and Mexico. It was announced to be in post-pandemic stages August 10, 2010. More than 200 regions across the globe have been affected by the virus.
  10. There have been more recent outbreaks of the disease. In 2015, India reportedly had over 31,000 people infected and 1,900 resulting deaths. There was a small outbreak in the Maldives in early 2017 with 185 reportedly having tested positive for the virus.

Vaccination is still the best protection against H1N1 influenza. Other measures can be taken, including hand washing, avoiding people showing symptoms and avoiding touching eyes, nose or mouth. It is also suggested to get vaccinated against the disease if traveling to an area where contracting H1N1 is a possibility.

– Drew Hazzard

Photo: Flickr

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10 Important Facts About Zoonoses and Initiatives Against Them


Zoonoses are diseases transferable between animals and humans. Zoonoses, or zoonotic diseases, have been recognized and studied for hundreds of years and remain a major concern for health and quality of life. Below are ten facts about zoonoses.

10 Important Facts About Zoonoses and Initiatives Against Them

  1. More than 200 zoonotic diseases have been identified. They are categorized by their causative pathogenic agent: bacteria, parasites, fungi and viruses.
  2. There are several ways that zoonotic diseases can spread. One method is through direct interaction with an infected animal or vector, such as a tick or mosquito. Direct contact occurs through bites, contact with fluids or excrements or even just petting an animal. Another means is through indirect contact. This is interacting with a medium such as soil, food or water that has been contaminated.
  3. Sixty percent of all human infectious diseases are considered zoonoses. An estimated 75 percent of emerging infectious diseases, which are infectious diseases that have been on the rise in recent decades, are transmitted from animals; examples include Ebola, HIV and influenza.
  4. The integrated effort to study interactions between animals, health and the environment is a field known as One Health. One Health examines the risks faced in both animal and human health, how they are influenced by their surrounding ecosystem and the resulting interactions that take place.
  5. Different zoonoses are more common in certain populations based on their typical interactions with livestock and the surrounding environment. Zoonotic diseases like trypanosome (sleeping sickness) and brucellosis, both of which are typically found in livestock, tend to occur in adults who occupationally engage with livestock. Often these individuals provide a great deal of support to their family, and the contraction of a zoonotic disease has serious effects, sometimes exacerbating the family’s poverty.
  6. The prevalence of zoonoses is not concentrated only in rural areas that rely on livestock or have unsanitary water; those living in urban slums also have a high risk of contracting a zoonotic disease due to the prevalence of animals that are not vaccinated or dewormed and unsanitary conditions. Because of the concentrated population and unsanitary living conditions in urban slums, those in urban poverty are also likely to contract multiple zoonotic diseases.
  7. Those in poverty are less likely to receive treatment for zoonoses. A large majority of the population that is at high risk for contracting zoonotic diseases lives in isolated rural areas far away from treatment facilities. Those in poverty often do not have access to diagnostic facilities or cannot afford the expense of laboratory work and tests necessary to diagnosis a zoonosis. Additionally, high-quality treatment for zoonoses are often expensive and in short supply; more affordable medication is often less effective and has serious side effects.
  8. One of the largest threats caused by zoonoses is food insecurity as a result of a loss of livestock due to disease and antimicrobial resistance. Antimicrobial resistance occurs in both animals and humans from the excessive or improper use of antimicrobial agents. Healthy animals are essential for the work and livelihood of millions of people around the globe as well as for food security.
  9. Addressing zoonoses is an essential component of global security. Eighty percent of agents that are deemed to have a potential for use in bioterrorism are zoonotic pathogens. The World Organization for Animal Health (OIE) encourages strong health monitoring systems for proper surveillance and prevention of zoonotic pathogens from being used as weapons.
  10. The OIE has several initiatives to reduce zoonoses worldwide. In 2011 rinderpest was eradicated. Currently, the OIE is focused on stamping out of foot and mouth disease, rabies and peste des petits ruminants. They have also established the World Animal Health Information System (WAHIS), which allows for global transparency, quicker notification of infectious outbreaks and easier access to health experts. Currently, 114 countries have reports posted on WAHIS.

Zoonoses are an important public health issue that requires multidisciplinary collaboration and strong health care systems. While they disproportionately affect those in poverty, these 10 facts on zoonoses outline the far-reaching effects of these pathogens and their relevance in all populations. Advocating for further attention to zoonotic diseases is an important public health initiative.

– Nicole Toomey

Photo: Flickr

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Top Diseases in Armenia


The country of Armenia, or the Republic of Armenia, is a sovereign state in the South Caucus region bordered by Turkey to the west, Georgia to the north, Azerbaijan to the east and Iran to the south. The Armenians are a rich and storied people dating back to antiquity.

Armenia has acted as a purely autonomous region since regaining independence from the Soviet Union after the fall of the communist party. Since the dissolution of the USSR, Armenia has had difficulties in maintaining quality healthcare for certain diseases due to a difficult transition from a centrally planned to a market economy. Due to this new economic redirection, the current healthcare system skews more toward funding hospital interventions, leaving little funding for community projects. Because of this, various communicable and non-communicable diseases have had a major impact on the people in this region. Here is a list of the top diseases in Armenia.

Non-communicable diseases

Like many countries in Europe, the most common cause of death due to illness is non-communicable diseases. Some of these diseases include cardiovascular disease, cancer, diabetes, chronic respiratory disease and musculoskeletal conditions. These all add up to a substantial fatality rate in the nation. Approximately 50 percent of deaths were caused by cardiovascular diseases and 74 percent resulted from combined symptoms (cardiovascular, neoplasms and diabetes mellitus) in 2013.

Malaria

Malaria is a disease spread by infectious mosquitos. It exhibits symptoms such as fever, vomiting and fatigue and can be fatal. Armenia was given malaria-free status in 2011 but has had a difficult time fighting the disease throughout the years. Thousands of people were infected between 1920 and 1930, and 200,000 cases were reported in 1934. Armenia was given malaria-free status in 1963 after years of fighting the disease. After the dissolution of the USSR, however, malaria resurfaced in 1994 and numbers peaked at 1156 in 1998. Cases have steadily decreased since, but malaria and yellow fever are still the top diseases in Armenia to look out for on the Center for Disease Control travel page.

Familial Mediterranean Fever

One of the top diseases in Armenia, Familial Mediterranean Fever (FMF) is hereditary and only affects individuals from the region. This disease is most common in people with Sephardic Jewish, Armenian, Arab and Turkish backgrounds. People infected generally exhibit recurrent cases of fever, abdominal inflammation, lung inflammation, swollen joints and a characteristic ankle rash. Severe cases of the disease can cause inflammation surrounding the heart (pericarditis) and swelling of the membrane surrounding the brain or spinal cord (meningitis). According to a report from the National Human Genome Research Institute, approximately one in every 200 people with one of these particular backgrounds has FMF. There is currently no cure for the disease.

Though there is still much work to do, Armenia has made significant strides in retooling its healthcare system. With the implementation of positive reforms, these top diseases in Armenia could be controlled or eliminated in the future.

– Drew Hazzard

Photo: Flickr

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Major Diseases in Croatia: Mostly Non-Communicable


Croatia is one of the smaller countries in the world with just over four million people currently living in the country. The average life expectancy in Croatia is 77 years, which is higher than the average life expectancy worldwide, which is 71 years according to the Institute for Health Metrics and Evaluation. Females are expected to live longer than the males in Croatia. The most major diseases in Croatia mostly contribute to deaths from an older age group.

The top two causes of deaths in Croatia pertain to the heart and the vascular system. Topping the list is ischemic heart disease (IHD), which caused 12 percent more deaths in 2015 than in 2005. IHD is the leading cause of premature death in Croatia, and it has held this spot for more than 10 years. In this way, IHD has become quite a large problem for Croatia. The second-highest cause of death in the country is cerebrovascular disease; it has maintained the second spot for years as well.

Cancer holds the next few spots on the list of top diseases in Croatia. One disease which has risen in prevalence in Croatia is Alzheimer’s disease, which kills 45 percent more people in the country than it did in 2005. Alzheimer’s has affected many people around the world, and it is now on the rise in Croatia as well. It has risen one spot on the list from fifth place to fourth place in the span of 10 years.

Rounding out the list of top diseases in Croatia is COPD, hypertensive heart disease, falls, diabetes and breast cancer. Falls are the only entry on the list that is an injury; the rest are non-communicable diseases. The most prevalent communicable disease on the list is the 14th entry: lower respiratory infections.

Risk factors in Croatia that can cause some of these diseases to begin or persist include dietary risks, high blood pressure and tobacco, alcohol and drug use, among others. These are major risks behind the list of premature and preventable deaths in Croatia.

When traveling to Croatia, there are many vaccines that should be up-to-date or received for the first time weeks in advance of the trip. These vaccines include those for hepatitis A and B, as well as the rabies vaccine.

The most prevalent diseases in Croatia mirror some of the major diseases found in other countries around the world. Cancers and heart diseases are some of the highest causes of death and disease worldwide. This is a trend that needs to be taken seriously, along with every other disease on the list.

– Brendin Axtman

Photo: Flickr

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Most Pervasive and Life-Threatening Diseases in Jordan


Since November 1998, the Centers for Disease Control and Prevention (CDC) has been cooperating with the Jordan Ministry of Health (MoH) to provide technical assistance and develop surveillance systems for health risk areas in Jordan. The systems track and analyze infectious diseases, mortality rates and risk factors for chronic non-communicable diseases.

The Institute for Health Metrics and Evaluation (IHME) is a private research center focused on calculating statistical population growth and health data. As a component of the University of Washington research institute, the IHME provides “comparable measurement of the world’s most important health problems and evaluates the strategies used to address them.” Jordan’s population (7.8 million) continues to rise, as well as chronic non-communicable diseases.

In 2015, the IHME reported 20,114 total deaths in Jordan, including all sexes and all ages. According to the center’s 2015 non-communicable disease statistics, the top diseases in Jordan are:

  • Ischemic heart disease
  • Cerebrovascular disease
  • Diabetes
  • Congenital defects
  • Chronic kidney disease

The top diseases in Jordan are primarily caused by high body-mass index, dietary risks, high fasting plasma glucose, tobacco smoke and elevated systolic blood pressure. Jordan’s top disease, Ischemic heart disease, is the cause of 15.98 percent of total deaths in the country and has remained in the top spot since 2005. The chronic disease occurs when the coronary arteries narrow, restricting blood and oxygen flow into the heart. Certain risk factors initiate the heart disease, damaging the inner layers of the coronary arteries. The primary culprit is smoking.

In 2013, the Tobacco Atlas reported that 43.3 percent of men and 8.5 percent women smoke tobacco in Jordan, both of which are higher than the average percent in middle-income countries. Smoking increases the likelihood of blood clots, reduces exercise tolerance, and increases blood pressure.

The CDC’s Field Epidemiology Training Program (FETP) has developed a system to successfully survey and analyze non-communicable diseases. Through the Behavioral Risk Factor Surveillance System (BRFSS), Jordan became the first Middle Eastern country to implement the program, which stemmed three national health surveys (2002, 2004, 2007). The program’s objectives are to progress the CDC’s global public health mission to respond to the high burden of noncommunicable diseases. By implementing the program, Jordan is one step closer to combating these hazardous diseases.

– Madison O’Connell

Photo: Flickr

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Top Diseases in Finland

finland
Finland is not one of the most populated countries in the world, but it is one of the more well-known. With just more than five and a half million people, Finland ranks 115th in population. The top diseases in Finland are also the major diseases found all around the world.

The World Health Organization (WHO) released a statement claiming that the top disease impacting the citizens of Finland is cardiovascular disease, contributing to 40 percent of fatalities in 2014.

Coming in second are other non-communicable diseases (NCD), at 25 percent. These diseases are very slow in progressing toward fatal levels. The four main types of NCD are cardiovascular disease, cancer, chronic respiratory diseases and diabetes. According to the WHO, they are the leading cause of death on a global scale, representing 63 percent of all deaths annually. Different categories of NCD kill over 36 million people each year, impacting predominantly low-income families, specifically those in less developed countries.

Other NCD making the the top list include various cancers (23 percent) and respiratory diseases (3 percent). Males have a higher chance of dying in each category than females. Over the last 15 years, the numbers for each category have been vastly decreasing due to new technology and procedures and treatments in the categories listed. Other major causes of premature death includes drug use, high blood pressure and obesity.

The smoking percentage in Finland is at 24 percent, which is higher than the U.S. percentage of 15 percent, according to the CDC. These are risks that can be completely eliminated by the individual’s efforts.

The top diseases in Finland mirror a lot of the top diseases around the globe. There is room for improvement based making healthy lifestyle changes and eliminating some of the risks factors including drug abuse and obesity.

– Brendin Axtman

Photo: Flickr

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Top Diseases in the Czech Republic


Modern medicine has rapidly developed over the past few years, but even today, diseases are still a major threat to many Europeans. Located in Eastern Europe, the Czech Republic is home to over 10 million people and, although poverty is at an all-time low, diseases in the Czech Republic still threaten its citizens. Data shows that the biggest threats are cardiovascular diseases, which take the lives of thousands every single year. Here is a list of the most threatening diseases in the Czech Republic.

Non-communicable Diseases

When breaking it down, non-communicable diseases make up more than 90 percent of the most harmful and deadliest diseases in the Czech Republic. From here, cardiovascular diseases make up for 48 percent of deadliest diseases, with cancer following second-most deadliest disease at 26 percent. Cancer is on a rise in the Czech Republic. For example, the mortality rate of pancreatic cancer has increased by 41 percent since 1990. Meanwhile, cardiovascular disease is actually decreasing. Ischemic Heart Disease has the highest mortality rate from the list of all diseases in the Czech Republic, but has luckily decreased by 25 percent over the past two decades. According to experts, poor diet, high systolic blood pressure and tobacco smoke are the most significant risk factors for Czech Republic citizens.

Communicable Diseases

Communicable diseases account for only a small percentage of deaths. Diarrhea, lower respiratory, and other common infectious diseases, which make up for 90 percent of communicable diseases, contribute only three percent to the deadliest diseases list. However, there have been sudden spikes in mortality rates for communicable diseases in the Czech Republic. The mortality rate for diarrheal diseases has increased by 307 percent between the years 1990 and 2013. Lower respiratory infections are only becoming more common.

Chronic Diseases and Obesity

The Organization for Economic Co-operation and Development (OECD) stated that the Czech Republic needs to work on both preventing and reducing chronic diseases. In particular, there are many chronic diseases in the Czech Republic that are caused by obesity. The rates of adult obesity have risen from 14 to 21 percent between the years 2000 and 2011. Obesity is causing fatal strokes and heart attacks, while also making many people develop diseases such as diabetes and heart disease. The prevalence of diabetes in the Czech Republic is about eight percent, which is higher than the OECD average.

The head of the OECD Health division, Francesca Colombo, stated that “The fact that obesity rates are higher than the OECD average and growing is very alarming.” She continues to explain that “The Czech Republic needs to renew its focus on programs that prevent disease.”

From communicable and non-communicable diseases, there is a lot of work to be done in order to prevent and reduce diseases in the Czech Republic.

– Morgan Leahy

Photo: Flickr