Information and news about disease category

Poverty in Angola
Despite its economic success in the booming oil industry, poverty in Angola is a serious concern. The fact that a majority of Angolans live in extreme poverty contrasts greatly with the country’s booming economy. Angola is one of Africa’s most resource-rich countries. It is the second-largest oil producer in Africa and the fourth-largest producer of diamonds. In addition, the country is rich in such resources as minerals, lumber and fish. Although the oil industry in Angola brings in a majority of the state’s revenue, two-thirds of the population live on less than $2 a day and do not see the benefits of the industry.

The government claims that poverty rates have dropped in recent years, yet corruption is still a major factor. The question remains: “Where is this money?” Government elites and employees reap the benefits of the oil industry, while many Angolans live in arduous conditions. Additionally, the country possesses high infant mortality rates, poor access to clean water and sanitation and high illiteracy rates.

The civil war from 1975 to 2002 left Angola devastated, with countless deaths and millions of internally displaced persons. Angola can now boast a revived economic situation and an up-and-coming international profile. However, the country still has a great deal of work to do in its commitment to alleviate poverty in Angola.

The 2016 Human Development Index ranks Angola 149 out of 186 on the poverty scale, as poverty permeates the entire nation. Poverty in Angola is greater in rural areas, which contains 38.5 percent of the population. In fact, 94 percent of rural households are categorized as poor.

There is a very low electrification rate in rural areas of Angola, with only 6% of rural households having access to electricity. A considerable amount of the population (38 percent) does not have access to safe water sources. Consequently, the mortality rate for children under five is around 17 percent. In addition, many children do not have access to education, making future employment difficult. In fact, 34.6 percent of people have unequal access to education. As a result, 28.9 percent of the population have an unequal income.

The capital city of Luanda, one of the largest cities in Angola, drastically contrasts its outskirts. Just outside the city limits, hundreds of thousands of people live in extreme poverty.With no running water or proper infrastructure for sanitation, disease runs rampant. Diarrheal diseases, cholera, measles and diphtheria are just a few such illnesses.

According to the World Health Organization, there were over 2,000 cholera outbreaks in 2009. Yet, there was only 1 doctor available for every 10,000 people. As a result, countless families lack access to vaccines or clinics to treat these diseases.

In recent years, there have been successful reconstruction programs, including roads, airports, bridges, hospitals and schools. Although the Angolan government is beginning to make progress towards rebuilding, the answer for widespread poverty alleviation lies within the ruling party and channeling the revenue from the oil industry into the hands of Angolan’s themselves.

Kimber Kraus

Photo: Flickr

Ebola VirusIn January, officials in Sierra Leone confirmed a new death from the Ebola virus in the country, days after Liberia, Sierra Leone and Guinea declared themselves Ebola-free.

According to NewsWeek, the World Health Organization (WHO) said last Thursday that “it was the first time all three West African countries had held the Ebola-free status simultaneously…effectively bringing to an end the deadliest Ebola outbreak in history that has claimed lives of some 11,300 people.”

The Ebola virus disease is a severe, often fatal illness in humans. It is transmitted to individuals from human to human transmission, or from wild animals. There are currently no licensed Ebola vaccines and the average EVD case fatality rate is around 50 percent, according to the WHO.

The Ebola outbreak in West Africa has been the largest and most complex outbreak since the deadly disease was first discovered in the late 70’s.

Said the WHO, “The most severely affected countries, Guinea, Liberia and Sierra Leone, have very weak health systems, lack human and infrastructural resources, and have only recently emerged from long periods of conflict and instability.”

A test center in Sierra Leone announced that the tests on the patient who died a few days ago confirmed that his death was due to the deadly virus. To reduce further threats, Sierra Leone officials are currently investigating how the individual became infected and who may have been in contact with him.

The World Health Organization also emphasized that future flare-ups of the deadly virus are probable.

Bruce Aylward, the Ebola correspondent in the organization said that the “risk of re-introduction of infection is diminishing as the virus gradually clears from the survivor population, but we still anticipate more flare-ups and must be prepared for them.”

According to NewsWeek, recent investigations have found that the virus can remain in the male survivor’s semen for up to nine months. Hence, the WHO suggests Ebola survivors and their sexual partners abstain from sex or practice extremely safe sex.

“There is as yet no proven treatment available for EVD. However, a range of potential treatments including blood products, immune therapies and drug therapies are currently being evaluated,” said the WHO. Additionally, two potential vaccines re undergoing human safety testing.

The World Health Organization suggests that in order to prevent and control this deadly threat, community engagement is the key to successfully control the outbreaks. “Raising awareness of risk factors for Ebola infection and protective measures that individuals can take is an effective way to reduce human transmission.”

Isabella Rolz

Sources: NewsWeek, World Health Organization
Photo: Bloomberg Business

Dengue FeverCountries in tropical climates, including Mexico and the Philippines, have started to approve the usage of a vaccine to prevent dengue fever.

Dengue fever is the most rapidly spreading mosquito-borne virus in the world today. The virus is currently present in 150 countries and over 390 million people are infected per year, with many cases being under-reported.

According to the World Health Organization, half of the world’s population is in danger of developing dengue fever. Patients inflicted with the disease are typically advised to rest, drink plenty of fluids and consume paracetamol, a widely used over-the-counter medicine to reduce fever.

Several tropical countries recently announced their plans to help prevent and reduce the number of dengue fever cases, with the world’s first dengue vaccine. Dengvaxia, a live attenuated version of the virus, will combat all four strains of the disease. The drug is scheduled to go on the market this month.

In the Philippines, health officials have started filing orders for Dengvaxia, aiming to bring the vaccine into its national market as soon as possible. Janette L. Garin, the Secretary of the Philippines Department of Health told GMA News that her country “is the only [location] where three phases of the clinical trial were done… it’s a reflection of how good our researchers are.”

Garin stated that officials will initially administer vaccines to students from eight to 10 years old, since they are the most likely candidates to fall victim to dengue fever. The vaccine is also less effective and more unpredictable in older patients.

“We don’t recommend it to [elder individuals] because there would be other interactions… That is why we want to play on the safe side,” Garin explained.

John Gilmore

Sources: GMA Network, WHO, Impatient Optimists, News Medical
Photo: Scientific American

Tuberculosis
Tuberculosis (TB) is responsible for 4,000 deaths daily, killing more adults around the world than any other infectious disease. Here are some key facts on TB:

  • According to the World Health Organization (WHO), 9.6 million people developed TB in 2014 and 1.5 million died as a result of the curable and preventable disease.
  • More than 95 percent of TB cases and deaths occur in developing countries.
  • Caused by bacteria, TB is spread from person to person through the air.
  • The WHO reports that about one-third of the world’s population has latent TB, meaning a person is infected by the bacteria but is not symptomatic and not transmitting the disease.
  • Between 2000 and 2014, an estimated 43 million lives were saved through TB diagnosis and treatment.

Tackling Multidrug-resistant TB

Unfortunately, after decades of use, anti-tuberculosis drug resistance is becoming widespread. Disease strains that are resistant to a single anti-TB drug have been documented in every country surveyed by WHO.

Multidrug-resistant tuberculosis (MDR-TB) is a form of TB caused by bacteria that do not respond to Isoniazid and Rifampicin, the two most common anti-TB drugs.

The primary cause of MDR-TB is inappropriate treatment. Inappropriate treatment ranges from an incorrect use of anti-TB drugs to the use of poor quality medicines.

“If we don’t act promptly, if we don’t act now, then the problem of drug-resistant TB will just get worse,” reported Peter Cegielski, team leader for Drug-Resistant TB and Infection Control in the global TB branch at the CDC.

The U.S. Agency for International Development (USAID) reported this year alone more than 480,000 people will develop MDR-TB and fewer than 20 percent will receive the medications they need.

The USAID responded to this global health concern by announcing two new partnerships to add resources and cutting-edge technology to fight drug-resistant tuberculosis.

Janssen, the pharmaceutical arm of Johnson & Johnson, announced a $15 to $20 million pledge to combat MDR-TB. Cepheid, a maker of molecular systems and tests, is also teaming with USAID in an effort to increase access to rapid, accurate diagnostic tools.

“USAID remains committed to addressing the global rise of MDR-TB,” Dr. Ariel Pablos-Méndez, USAID Assistant Administrator for Global Health, said. “With the successful implementation of this plan, we have an incredible opportunity to make a significant impact on the emergence and spread of MDR-TB. We will continue to harness mutually rewarding partnerships, like the ones with Janssen and Cepheid, to lead international efforts against MDR-TB.”

Kara Buckley

Sources: USAID, VOA News, WHO
Photo: All Africa

Smartphones_Healthcare Disease DetectionDr. Aydogan Ozcan is revolutionizing disease detection and diagnosis. The electrical engineer and bioengineer from the University of California, Los Angeles has developed a microscope that utilizes smartphones.

Smartphones seem a simple alternative to expensive lab equipment. “We have close to six billion cell phone subscribers today,” Ozcan said on the timeliness of his development. Of these users, 70 percent come from developing countries that have a greater need for this microscope.

The system weighs about 200 grams and is able to identify particles as small as 100 nanometers. According to Charles Choi of Scientific American, the microscope can also detect relatively large viruses like HIV and harmful bacteria present in food and water.

The device is easy to use, which means more people can use the smartphone microscope for their benefit. The portability and cost-effectiveness of the device may prove invaluable in remote areas without easy access to medical facilities or trained personnel.

How exactly does the microscope function?

Instead of lenses, this device creates images electronically, according to a New York Times article by Anne Eisenberg. Choi explains that molecules known as fluorophores “[that] fluoresce under certain wavelengths of light” identify and locate the target particles to which they attach.

A blue laser shined onto the particles excites them, creating a hologram from which information can be extracted. The hologram may prove quicker than microscopes in disease detection and diagnosis, according to Eisenberg.

This speed and effectiveness could play a crucial role in future research by, for instance, facilitating the screening of entire regions. This could help gather information on how diseases spread and subsequently inform future responses, Ozcan said.

Ozcan continues to develop his research for the betterment of global healthcare. Holomic LLC, a start-up he founded, “aims to commercialize the computational microscopy.” Commercialization may give his and similar innovations a greater reach and applicability.

Jocelyn Lim

Sources: Anna Eisenberg, Charles Q. Choi, Holomic, National Geographic, Biophototonics
Picture: Google Images

Trachoma_TreatmentAccording to the International Trachoma Initiative (ITI), trachoma remains the world’s leading infectious cause of blindness. Pfizer Inc., along with several partners has been working to provide critical trachoma treatment, particularly for patients in developing countries.

What is Trachoma?

Trachoma is an infectious disease caused by bacteria. It is spread through contact with eye discharge from an infected person – via hands, towels, sheets and in some cases, eye-seeking flies. The infection thrives in areas with poor sanitation and limited access to water for personal hygiene.

Without treatment, trachoma develops into a condition called trichiasis. Trichiasis causes the upper eyelids to turn inwards and scrape the eyeball, a painful condition that eventually leads to blindness.

In 2014, the World Health Organization (WHO) estimated that 232 million people were at risk of developing trachoma. Studies indicate that trachoma is endemic in 51 countries with more than 80 percent of sufferers concentrated in 14 countries.

To help combat the spread of trachoma, Pfizer along with ITI and the International Coalition for Trachoma Control announced the corporation’s 500 millionth donation of the tablet Zithromax, a trachoma treatment antibiotic used in countries across Africa and Asia.

The partners are working together as part of an Alliance for the Global Elimination of Trachoma by 2020 (GET 2020) led by the WHO. The Alliance is an expansive collaboration of more than 100 governments, non-governmental organizations and private sector partners.

The SAFE Strategy

Together the group has implemented a WHO recommended strategy called SAFE:

Surgery to treat the blinding stage of the disease

Antibiotics to treat infection

Facial cleanliness to help reduce transmission, and

Environmental improvement including access to water and sanitation.

 

ITI pointed out trachoma was once endemic in Europe and the United States. Before the use of antibiotics, trachoma disappeared due to improved living standards.

Today, antibiotic treatment provides a short-term cure, especially when the whole community is treated. However, reinfection can occur, typically within six months if hygiene and the environment don’t improve. For this reason, it is essential that the full SAFE strategy is in place in trachoma-endemic communities.

Paul Emerson, the Director for ITI said, “Trachoma traditionally affects the people at the end of the road, they’re the forgotten people, they are people with a very little political voice. Because trachoma is a hidden disease it is very difficult for people to care. Well, we do care. And we want to reach all of those people.”

Kara Buckley

Sources: Carter Center, Sight Savers, Trachoma Coalition, Trachoma.org
Photo: Google Images

Mosquito_net_in_Subsaharan_AfricaAccording to the World Health Organization (WHO), approximately 3 billion people across the globe are at risk for contracting malaria. One-third of this group is considered to be at high risk and 90 percent of malaria deaths occur in Africa.

NetsforLife Steps In

NetsforLife is working to reduce the number of malaria deaths in Africa. Since its inception in 2005, this partnership of corporations, foundations, NGOs and faith-based organizations has distributed nearly 22 million mosquito nets in 17 malaria-endemic countries of sub-Saharan Africa.

However, the organization’s efforts to eradicate malaria extend beyond net distribution. According to its website, NetsforLife also ensures that communities receive adequate training on the value of these nets as well as “the right way to use and maintain them.”

Too often, mosquito nets have been used for fishing or as bridal veils instead of the vital purpose for which they were created.

In addition to educating communities on the proper use of nets, the organization also specifically targets remote areas that typically do not receive care from national healthcare systems.

NetsforLife calls on the help of local leaders and community volunteers or “malaria agents” to provide the necessary education and support to civilians.

Malaria Prevention is Key

According to the WHO, prevention is an important aspect of combatting malaria. The malaria parasite, Plasmodium, multiplies quickly, allowing it to build up resistance to malaria medicines. Mosquito nets and more specifically, insecticide-treated nets (ITNs), play a crucial role in prevention efforts.

While significant headway has already been made with the number of malaria cases declining to 214 million in 2015 from 262 million in 2000, there is still much work left to be done to eradicate the disease. To that end, the WHO launched “The Global Technical Strategy for Malaria, 2016 – 2030” which aims to reduce malaria incidence and mortality by 90 percent.

With over 100,000 volunteers, NetsforLife continues to do its part to help achieve these goals. So far, the organization has reached 41.7 million individuals and counting.

Jocelyn Lim

Sources: NY Times, NetsforLife, World Health Organization (WHO) 1, World Health Organization (WHO) 2, World Health Organization (WHO) 3
Photo: Google Images

Global_Health_Security_Agenda
The U.S. along with 30 countries has announced a commitment to achieving the targets of the Global Health Security Agenda (GHSA). Targets include responding to infectious disease threats and preventing epidemics.

The GHSA “seek[s] to accelerate progress toward a world that is safe and secure from infectious disease threats and to promote global health security as an international security priority,” GlobalHealth.gov said.

The Agenda was created in response to epidemic threats, such as ebola and seeks to promote global health and protect citizens around the world from life-threatening diseases.

The 30 countries that the U.S. has partnered with are: Bangladesh, Burkina Faso, Cambodia, Cameroon, Cote d’Ivoire, Democratic Republic of Congo, Ethiopia, Georgia, Ghana, Guinea, Haiti, India, Indonesia, Jordan, Kazakhstan, Kenya, Laos, Liberia, Mali, Mozambique, Pakistan, Peru, Rwanda, Senegal, Sierra Leone, Tanzania, Thailand, Uganda, Ukraine, and Vietnam, as well as the Caribbean Community.

The commitment includes a five-year country roadmap that will detail practical plans for the GHSA.

“These roadmaps are intended to enable a better understanding across sectors and assistance providers of the specific milestones, next steps, and gaps toward achieving capacity needed to prevent, detect, and respond to biological threats,” the White House said in a press release.

The countries involved seek to collaborate on a global issue that impacts millions of people in developing areas. Infrastructure, equipment and skilled personnel are some of the resources that the GHSA partnership plans to provide.

During this year’s G-7 Summit in Germany, G-7 leaders committed to collectively assisting at least 60 countries, including the countries of West Africa, over the next five years. The G-7 Health Ministers agreed to announce these countries by the end of this year according to the White House.

This collaboration provides a bright spot for the future. Health security is a huge issue today, as infectious diseases kill over 17 million people a year. At least 30 new diseases have emerged in the last 20 years, and they all require attention and research in order for cures to be discovered according to the World Health Organization.

Next year’s GHSA event will be hosted by the Netherlands and will highlight progress and continue to build momentum on these issues.

Ashley Tressel

Sources: White House, WHO, Global Health
Photo: Flickr

10665321703_346e1b8ea7_z
A new experimental drug treatment given to cattle in Uganda has cut the sleeping sickness cattle infection rate by 75 percent, which means fewer humans are getting infected. The drug is a dual treatment that kills both the parasites that cause sleeping sickness and the flies that carry them.

The sleeping sickness, also known as African Trypanosomiasis, is transmitted through bites from tsetse flies, which are prevalent in the rural areas of sub-Saharan African countries.

The human pathogenic parasites that cause the sleeping sickness can be harbored by both humans and animals. However, only certain tsetse flies can carry the parasite.

The campaign to end the epidemic of sleeping sickness in northern Uganda started in 2006 and was led by Dr. Susan Welburn, a zoonotic disease specialist at the University of Edinburgh, Scotland. At the time, two types of trypanosome parasites overlapped geographically, killing more than 100 people per day.

Dr. Welburn and her researchers, in partnership with the veterinary school of Uganda’s Makerere University, injected more than 400,000 cows in seven rural districts with the anti-parasitic drug Veridium. To prevent fly bites they sprayed the legs, bellies and ears of the cattle with a long-lasting insecticide called Vectocid.

The researchers have set up small-scale local businesses that provide the preventative treatment for farmers. Dr. Welburn admits it has been a challenge to convince farmers to herd their cows to get treatment, as cattle infected with sleeping sickness parasites do not show symptoms.

“The disease has moved into eight new districts in Uganda in as many years as people travel more and sell their cattle across the country,” Dr. Welburn said.

Dr. Welburn predicts that eradicating sleeping sickness will take eight years of constant treatment. “It would require dedicated management from the government,” she said. “That’s why this project needs to break away from scientists and be owned by the community.”

The team plans to expand its treatment across Uganda to 2.7 million cattle.

Marie Helene Ngom

Sources: NYtimes, WHO, SciDevNet
Photo: Flickr

CFHI
Less than half of the population in Uganda has access to health care. In addition, the country suffers from a deficit of 1.5 million health workers. It is therefore not surprising that treatable diseases are the leading cause of death in Uganda.

The government created the Village Health Team program in 2001 to focus on the lack of health workers. The joint program “Community Health Workers & Global Health” will be based in Uganda’s Mukono District, 13 miles from the capital Kampala. The Child Family Health International organization offers global health education programs that “broaden students’ perspective on global health.”

Child Family Health International (CFHI) is partnering with Omni Med to expand health care capacity from rural to central Uganda. This expansion will improve Omni Med’s training and surveillance of Village Health Team and allow participants to assist the locally-led capacity building and quality assurance.

Omni Med began its work in Uganda in 2008 and has since trained over 1,200 community health workers and established protected water sources and cookstoves as well as distributing insecticide-treated nets. These teams include health educators in rural villages who make a big difference in the health of the world’s poorest people.

Village Health Teams are elected by local villagers and tasked with educating locals with preventative health information, referring sick people to health care centers and tracking health trends for Uganda’s Ministry of Health.

Child Family Health International Global Health Scholars, also known as participants, will assist the Village Health Teams in providing locals in rural Mukono with the best preventative tool: knowledge.

Scholars will accompany the teams on their home visits, train and maintain the team’s health knowledge by teaching in quarterly meetings and aiding in other Omni Med local activities.

“We believe strongly that it is not enough to feel good about what we do–we have to measure the impact we make, and then adjust our programs based on the data,” president and founder of Omni Med, Dr. Ed O’Neil Jr said.

Marie Helene Ngom

Sources: PRweb, CFHI
Photo: Flickr