Information and news about disease category

Infectious Diseases in Madagascar
Madagascar is an island country off the southeastern coast of Africa. It is famous for its unique climate, vibrant ecosystems and a Disney movie bearing its namesake. However, despite its colorful outward appearance Madagascar is not only a country that has been struggling with the burdens of extreme poverty. It is also a country that has strived to respond to the constant risks of infectious diseases in Madagascar that are rampant throughout its population.

5 Facts About Infectious Diseases in Madagascar

  1. Of the top 10 leading causes of death in Madagascar, four are infectious diseases. Compared to the United States, which only has one infectious disease in its top 10 causes of death, Madagascar’s rate of death due to these largely preventable illnesses is staggering. These four killers are diarrheal diseases, lower respiratory infections, malaria and tuberculosis. Diarrheal diseases and lower respiratory infections, the top two leading causes of death in Madagascar, are not on the lists of countries such as the United States. Easily preventable simply through clean water and relatively basic medical equipment and treatment, these infectious diseases are just one of many lethal circumstances stemming from poverty.
  2. More than 60% of the population of Madagascar lives far from health centers. Additionally, the methods of travel are dangerous and difficult. Underdeveloped and often undermanaged roads and means of travel are when coupled with the scarcity of adequate care, literally a hard road to health. All four of the leading causes of death by infectious diseases are prevalent in Madagascar are preventable and treatable given adequate recovery time, proper equipment, medication and access to proper nutrition. However, if travel is expensive and exhausting those in need will not have the time or resources to spare to travel to one of these remote health care facilities.
  3. Diarrheal diseases are the leading cause of death in Madagascar. According to the World Health Organization (WHO), in 2018, diarrheal diseases were responsible for 10,832 deaths or 7.88% of deaths in Madagascar. These diseases are particularly deadly due to the high rates of malnutrition in the population. Diarrheal diseases are especially draining and resource-heavy upon one’s body and for those without healthy and consistent diets coupled with the lack of potable water and adequate hygiene that may have caused the disease in the first place. Although attention for this issue is very minimal, there are efforts to help the people of Madagascar prevent these diseases through the allocation of health hygiene products and the spread of health information. Project WASH Madagascar provides information to children and adults about the importance of cleaning their hands and drinking clean water. It has been distributing WASH kits that contain additional information as well as cleaning products.
  4. Malaria rates have been steadily climbing since 2009. Deaths due to malaria in Madagascar increased by 7.5%, between 2009 and 2019. The United Nations OCHA reported an increase of malaria cases from 402,385 in 2019 to 663,558 in 2020. This may be partly due to the decrease in incoming aid and available health services during the COVID-19 pandemic. Malaria is an infectious disease that, with the proper resources, is entirely preventable and treatable. However, just as with these other infectious diseases, circumstances from poverty block the road to health and kill thousands.
  5. After a measles outbreak in 2018 – 2019, infection and death rates are almost completely down. Madagascar has been struggling to address these issues even amidst the hectic state of the world. However, it is important to acknowledge the successes that Madagascar has seen through coordination between The Ministry of Public Health and WHO and partners in combating these infectious diseases. The distribution of vaccines led to vaccine information, education and free emergency care to those in critical condition, helping control the outbreak. Between January and April of 2019, 46,187 people became infected with measles and 800 dead during a widespread measles outbreak. Medical science and collective human effort contained the measles outbreak with only 34 cases since January 2020, according to Outbreak News Today.

Looking Ahead

As the world collectively becomes intimately aware of the threats of infectious diseases, especially in cases where there is no supporting health infrastructure, the circumstances of people like those in Madagascar become plainly dire. There are measures to take and aid to disperse that would solve many of these problems. While there is a long way to go, Madagascar continues to work in the hopes of preserving its people and ensuring their safety.

– John J. Lee
Photo: Fickr

disease response in the DRC
The Democratic Republic of Congo (DRC) “has the third-largest population of [impoverished people] globally.” The coronavirus has hit the DRC’s economy hard, further reducing the country’s capacity to fight disease. One advancement in disease response in the DRC is the government’s use of mobile phone data for population mapping, which helps create public health policies for COVID-19 and could do the same for other prevalent diseases in the country in the future.

Ties Between Disease, War, Poverty and COVID-19 in the DRC

The DRC has historically faced challenges in combatting cholera, malaria, HIV, measles, Ebola and Rift Valley fever. Factors contributing to the challenges in combatting disease include a weak health care system, low laboratory capacity, a lack of plans regarding border lockdowns for disease containment and a lack of information about vaccination and disease prevention for the public.

Additionally, the DRC endured a civil war from 1997 to 2003. The civil war ravaged the country’s infrastructure and the ongoing political instability in the country currently poses obstacles for aid workers to safely enter the country. The effects of the civil war also reduce the government’s ability to fight prevalent diseases in the DRC.

Furthermore, in 2019, the DRC’s economic growth stood at 4.4%. After the COVID-19 pandemic began, the DRC’s economic growth shrank to 0.8% in 2020. The slowdown in economic growth has made it even more difficult for improved disease response in the DRC.

Using Mobile Phones to Combat COVID-19

Low-income countries, including the DRC, struggle with data collection. However, data collection is vital in order to provide government officials with information to make sound public health decisions. The good news is that the DRC is starting to utilize mobile phone data for population mapping to combat COVID-19, which could greatly improve the DRC’s response to other diseases as well.

Orange DRC, a telecommunications company, provides anonymized mobile phone data to a marketing company called Kinshasa Digital. Using the phone data, Kinshasa Digital is constructing a dashboard for the DRC so that health officials can follow population movement after implementing various public health policies. The dashboard is useful because it allows the government to follow the spread of COVID-19 and use this data to create policies that will be most beneficial for the public’s health.

Data-Informed Responses

In addition, Vodacom DRC, a mobile carrier, and Flowminder, a company that analyzes mobile data, have created a report utilizing call detail records that analyzes how population movement patterns in Kinshasa’s Gombe district have changed in response to the DRC’s COVID-19 confinement policies. The report indicates “a drop of 70% in the total flow of subscribers traveling to Gombe after the confinement,” which shows that many people are complying with the government’s policies.

The creators shared the report with government officials. Reports like these can help the government measure how effective its public health policies are. As the technology and analytics industries develop, these reports can further improve the government’s response to COVID-19 and possibly other diseases too.

The DRC faces challenges in disease response, but the current innovation with mobile phone data to create more effective COVID-19 policies shows a promising development. As mobile phone companies, analytics companies and the government continue to work together, disease response in the DRC as a whole could greatly improve.

– Anna Ryu
Photo: Unsplash

Kidney Disease in Southeast Asia
End-stage renal disease, the last stage in chronic kidney disease, is one the deadliest illnesses in the modern world. This rise in end-stage renal disease can result in a considerable loss of economic growth and cause a massive loss of life. Growing countries and communities experience a harsher result from end-stage renal disease. Southeastern Asian countries face challenges that are damaging to poverty-stricken countries. Many vulnerable individuals face the challenging task of securing medical assistance for combating chronic kidney disease because of healthcare systems lacking financial support, including renal support. The 21st century has brought to light a new, dangerous illness. The process of combatting kidney disease in Southeast Asia must occur through global initiatives and support.

The Silent Chronic Illness

The term “silent illness” is a long-term sickness that results in death. Chronic kidney disease, known as CKD, is one of the deadliest diseases globally, killing millions each year. With more than 10% of the population suffering from the disease, its lethality has grown sharply. It increased from the 28th deadliest cause of death to the 19th. This sharp rise in death rate is comparable to only AIDS, and HIV has a sharper increase in death rate. This statistic showcases the challenges in combating kidney disease.

A recent study from the scholarly journal, Nephron Clinical Practice, displayed the significant financial and medical expenses that could come from the sharp rise in kidney disease illnesses and deaths. These issues will hit developing countries the hardest. More than 23 developing countries could lose more than $85 million in economic development. Southeast Asian countries suffer the worst. Renal Replacement Therapy costs 10 times as much as the per capita income. Furthermore, very few medical coverages support renal medical treatment. Only 10% of individuals suffering from chronic kidney disease have access to renal medical resources, a worrying statistic for the future of developing countries that work hand in hand with other developed countries to continue to flourish against kidney disease in Southeast Asia.

Kidney Disease in Southeast Asia

Kidney disease preventative centers and policies are not very accessible in Southeast Asia. Many governments have just become aware of the extensive and damaging results that kidney disease carries. Southeast Asian countries lack the essential resources to help with a deficiency of dialysis treatment.

This disease is, however, especially deadly in impoverished communities worldwide. Experts from The International Society of Nephrology, the world’s leader in chronic kidney disease research, found in a recent study that more than 10 million people die every year from chronic kidney disease. The BNC Nephrology systematic review also saw a sharp decline in human resources in kidney services and disproportionate effort within the healthcare system of these respective Southeast Asian countries.

Combative Practices

Political and social policies have always provided support to those who need it. However, recent years have been more optimistic towards a more renal secured Southeast Asia. One country that has doubled down on this matter has been Thailand. In the past decade, Thailand has created three new national kidney foundations. The kidney foundations work through direct financial and medical support to those most in need and politicians to secure a poverty-ending medical support policy for those at risk and suffer from chronic kidney disease.

Some are working on the introduction of a renal replacement therapy policy within Southeast Asia today, with help from the International Society of Nephrology. The society is holding various forums to work with the Southeast Asian governments for more inclusive policies.

Malaysia and the Philippines both have two national kidney foundations to educate and secure funds needs for renal therapy and medical support. Consequently, the increase of chronic kidney patients has increased the demand for dialysis nurses and doctors.

Malaysia, Thailand and Singapore are receiving public-private partnerships in supporting renal therapy and medical support. The acknowledgment of policies that allow further funding from private organizations and liberal implementations of new policies would also trigger community involvement, drafting a new healthcare system with the inclusion of kidney care to combating the rise of kidney disease in Southeast Asia.


Chronic kidney disease has been dismantling families and hitting poverty-stricken communities the hardest. Southeast Asian communities have followed a pattern in renal disease medical needs. Millions of people with and without preexisting conditions are at risk. But, Southeast Asia can become a much more healthy and prosperous place for those who suffer from chronic renal disease. Combating kidney disease in Southeast Asia will continue to be an uphill battle. However, the next generation of policy for a healthier healthcare program will usher in a new era of kidney care for those most at risk in Southeast Asia.

Mario Perales
Photo: Flickr

disease in Sub-Saharan Africa
The threat of disease transmission plays a significant role in the life of sub-Saharan Africans. Diseases such as malaria, HIV/AIDS, tuberculosis, heart disease and diarrheal diseases remain leading causes of death for African citizens. Of particular worry is HIV/AIDS, the fourth leading cause of death on the continent. Furthermore, urbanization has direct links with reducing disease in sub-Saharan Africa. The United Nations Programme on HIV/AIDS estimates that 25.5 million people currently live with HIV/AIDs in sub-Saharan Africa, representing approximately 64% of the world’s cases. The transmission rate is particularly high in sub-Saharan Africa due to high rates of poverty, with over 60% of the population spending less than $1 a day.

Fortunately, in recent years, sub-Saharan Africa has witnessed a downturn in disease trends. For example, in the last six years, Africa has reduced AIDS deaths by over 30%. One can partly explain the successes in stopping the transmission of disease in sub-Saharan Africa by the process of urbanization that sub-Saharan Africa has undergone in recent years. Physician’s Medical Center Labs explains this relationship, highlighting factors such as sex work, migration, polygamy and teenage marriages, all of which increase with higher poverty levels.

What is Urbanization?

Urbanization is the process of making an area more urban. Characteristics defining urban areas include higher population density, greater infrastructure and non-agricultural opportunities for specialization. Urbanization has been ongoing since the 1950s in sub-Saharan Africa – however, its pace has increased in the past few decades. The rate of urbanization in sub-Saharan Africa is the highest globally, with an average annual growth rate of 4.1%. Urban growth results from a multitude of factors, including migration and the reclassification of cities. Migration from rural areas to urban centers is predominantly based on educational and financial concerns.  However, seasonal and forced migration can also play a role in the growth of urban centers. This fast-paced urbanization is not without its challenges, including income loss, weak investment and less productivity. Nevertheless, urban areas can create circumstances that can reduce the transmission of disease in sub-Saharan Africa.

Improving Sanitation

Improved sanitation follows urbanization. Even in the most impoverished urban areas, sanitation conditions are still better than those in rural communities. The key factors contributing to sanitation levels are clean water and flush toilets. Poor urban areas remain two times more likely to have clean, piped water. They are also four times more likely to have flush toilets than rural areas. This is vital to disease prevention as poor sanitation in human waste is a key driver of disease transmission, specifically diarrheal diseases. Piped water can also reduce the threat of mosquito growth. Large amounts of stagnant water provide breeding grounds for dangerous mosquitos, which transmit viruses such as malaria. Piped water decreases the need for stagnant storage sites, diminishing this problem.

Empowering Women

Urban areas provide greater educational opportunities. While schools in rural areas remain understaffed, urban schools can cater to more students with a higher quality of education. This access to education is essential for females as women are 20% more likely to attend school in urban areas. Education for women is key to increasing awareness of sexual health needs and reproductive control. Along with education, the increase in infrastructure that results from urbanization can also increase access to resources for women. They can access the clinics and facilities necessary to control their fertility and protect themselves during sex. This is especially important for female sex workers in the region. In urban areas, the infrastructure of clinics, reproductive health resources and educational opportunities provide women with solutions that can decrease the prevalence of sexually transmitted diseases and infections.

Tracing Diseases

Urbanized areas have the infrastructure necessary to support cell towers and the internet. Because of this infrastructure growth, urban settings allow for high rates of cell phone usage. Meanwhile, rural areas tend to lack access to personal technology devices. In South Africa, around 50% of the rural population do not have access to a personal cellular device. The increased prevalence of mobile phones in urbanizing areas could play a consequential role in combating disease transmission in sub-Saharan Africa. The success of mobile phone contact tracing apps that some utilized during the COVID-19 pandemic highlights this. A Massachusetts Institute of Technology study has found that these apps can decrease the infection rate and break transmission chains even with limited use. People could utilize these tools, thanks to urbanization, to decrease the transmission of disease in sub-Saharan Africa.

US Foreign Assistance is Vital

When looking at the benefits of urbanization throughout the world, it is important to focus on the dangers it can present. While urbanization can foster gender equality, education and quality healthcare, poorly managed urbanization can worsen inequality and destabilize governments. The work of U.S. Foreign Assistance plays a consequential role in the lives of Africa’s urban population. However, U.S. assistance remains disproportionately focused on rural settings, leaving these urbanizing areas in danger. Thus, the continued role of the U.S. in supporting poverty reduction initiatives throughout sub-Saharan Africa is vital to support and foster long-term, stable urbanized growth. One cannot discount the role of urbanization to impede the transmission of disease in sub-Saharan Africa.

Haylee Ann Ramsey-Code
Photo: Unsplash

How Neglected Tropical Diseases Contribute to PovertyProminent diseases that affect developing countries receive little donor funding due to their lack of presence in more developed nations. As a result, over one billion people living in developing nations become infected by diseases. However, the rate of infection is higher in developing, tropical countries. Neglected tropical diseases are caused by a variety of viruses, bacteria and parasites.

Neglected Tropical Diseases

Diseases such as malaria, HIV and tuberculosis that do not receive adequate attention or funding are known as neglected tropical diseases. According to the World Health Organization, more than two billion people are at risk of such diseases. Lack of treatment for these diseases can result in blindness, developmental disabilities and malnutrition.

Common Neglected Tropical Diseases

  • Dengue fever: This disease is contracted through mosquitos, resulting in serious joint and muscle pain.
  • Ascariasis: As a result of a parasitic worm and unsanitary conditions, this disease usually has mild symptoms. However, with a high amount of worm infestation, the side effects can be more severe. More serious symptoms include abdominal pains, vomiting and even death.
  • Hookworm: This disease is contracted by walking barefoot on soil tainted with a significant amount of feces.
  • Leprosy: This infectious disease can lead to permanent damage to the skin, nerves, limbs and eyes.
  • Trachoma: This bacterial disease leads to scarring on the inside of the eyelid that can cause blindness if left untreated.

Neglected tropical diseases flourish in areas with high levels of poverty due to the lack of access to clean water and sanitation. Additionally, the detrimental effects of these diseases create a decline in school enrollment and limit work productivity.

Prevention Methods

The best way to fight neglected tropical diseases is through prevention. Here are some ways to prevent such diseases in developing countries.

  • Improved sanitation: Clean access to water, improved food handling measures and better hygiene can prevent diseases such as guinea worm disease, schistosomiasis, soil-transmitted helminthiasis and trachoma.
  • Controlling vectors: Diseases that are spread by hosts can be prevented by managing the vectors. One method is significant insecticide spraying in areas where vectors gather and reproduce, killing bacteria become hosts and carriers.
  • Education programs: Educating people who are more vulnerable to these diseases greatly aids in prevention efforts. Through education programs, at-risk communities can learn how to limit the risk of infection. For example, communities can limit the number of diseases brought by mosquitoes by reducing standing water areas. Furthermore, sleeping under a bed net reduces the risk of contracting diseases carried by flies.

Bringing Awareness

Providing a platform to bring more awareness to neglected tropical diseases is vital in fighting them. The Neglected Tropical Diseases NGO Network, founded in 2009, provides opportunities for different NGOs to work together to find solutions to these diseases. The SCI Foundation, The Partnership for Child Development and Water Aid are just a few NGOs that are a part of the network.

Programs and Forums like The Neglected Tropical Diseases NGO Network play an essential role in gaining the attention and funding required to aid impoverished areas. Working to prevent these diseases also helps to reduce poverty. Millions of people suffer from these debilitating diseases, and spreading awareness is a small thing that can lead to big change.

– Celia Brocker
Photo: Flickr

One Health
For those living in wealthy nations, infectious diseases and foodborne illnesses are typically an inconvenience. Improvements in healthcare technology, including widespread vaccinations for once-deadly diseases, can render events such as the COVID-19 pandemic seemingly rare. However, in low-income nations, this is not the case. Around 420,000 people die each year from foodborne illnesses, most commonly children under 5 years old in Africa and Southeast Asia. Here is some information about the causes of disease outbreaks worldwide and the means of disease prevention that people know as One Health.

The Situation

Infectious disease outbreaks have increased significantly from 1980 and include SARS, H1N1, Ebola, MERS, Zika and COVID-19. Additionally, up to 75% of new infectious diseases are zoonotic, meaning they begin in animals and transfer to humans. Some animals, such as bats, are resistant to becoming ill and easily spread diseases that lie dormant in their immune systems.

Zoonoses are more and more common as humans become further integrated with the natural world. Reasons for the increase of zoonoses include:

  • Deforestation and Mining: Deforestation and mining destroy habitats and force animal populations closer to civilization. The World Economic Forum estimates that 31% of infectious outbreaks have a link to deforestation.
  • Urbanization: Urbanization can foster the dominance of disease-prone species such as white-footed mice.
  • Factory Farming: Factory farming harbors large populations of genetically similar animals in unsanitary conditions that are susceptible to disease outbreaks.
  • Wet Markets: Wet market merchants often bring exotic species out of their habitats and near humans.
  • Tourism of Wildlife: Tourism of wildlife, such as caves that contain bats, risks spreading diseases to humans.
  • Bacterial Infections and Antibiotics: While bacterial infections currently pose a minor threat due to the widespread availability of antibiotics, experts warn that modern animal agriculture practices, where farmers give antibiotics to livestock in large doses, are rapidly breeding strains of bacterial diseases resistant to antibiotics. Many of these strains are beginning to pose a threat in medical treatment practices.

One Health

Between foodborne illnesses, antibiotic resistance and zoonotic diseases, it is clear that the well-being of animals closely ties with the well-being of humans. This perspective of disease prevention is known as One Health. The One Health model necessitates considering major environmental and agricultural policy shifts, but people are already taking small steps to directly reduce disease transmission. Health agencies around the world are holding conferences to prioritize zoonotic disease prevention and conducting investigations into the origins of outbreaks.

In Thailand, a team of software developers launched a movement to monitor animal illnesses and contain possible outbreaks of zoonoses. Since 75% of rural Thai households have backyard animals, disease transfer is a major concern. The project, called Participatory One Health Disease Detection, consists of 3,000 volunteers using a smartphone app to report information about sick and dead animals to the project developers, who are veterinarians at Chiang Mai University. The developers are able to detect, investigate and quarantine potential outbreak risks. According to the Gates Foundation, an infectious disease could spread to every global capital in just 60 days, so detecting an outbreak early could save thousands of lives.

Keeping the human population safe from deadly diseases means acknowledging the connections between civilization and animal habitats, especially in high-poverty areas where habitat destruction from resource extraction such as deforestation and mining means that line increasingly blurs. The One Health model sets short-term and long-term goals for monitoring and restoring the health and safety of animals and the natural world.

– Elise Brehob
Photo: Flickr

Hemophilia in Kenya
Around 5,000 Kenyans suffer from a blood disorder called hemophilia. Hemophilia prevents blood clots from forming after a wound and results in continuous bleeding. Many Kenyans with this disorder often pass away due to the inability to pay for treatment. Also, stigma from local communities makes individuals believe that hemophilia comes from witchcraft and it prevents affected Kenyans from finding traditional Western medicine. The World Federation of Hemophilia (WFH) Humanitarian Aid Program, Muranga Hospital and Save One Life offer free medical treatment to low-income patients, give grants to fund small businesses, host gatherings to encourage peer support and provide education and awareness about hemophilia in Kenya.

The World Federation of Hemophilia (WFH) Humanitarian Aid Program

WFH started helping out in Kenya in 2015 and strives to provide medical treatment to lower-income individuals with hemophilia. Since arriving in Kenya, the program donated more than 17 million international units of factor to Kenyans. This treatment allows patients with acute bleeding to find temporary relief.

With the consistent flow of clotting factor coming into Kenya, young children qualify for prophylactic treatment. WFH offers prophylactic treatment to children with hemophilia to reduce the risk of bleeding and joint damage in the future. Children who were on the verge of dropping out of school due to their disorder continued with their education after receiving treatment.

Muranga Hospital

Located in central Kenya, the Muranga Hospital dedicated a special clinic to treat patients with hemophilia in Kenya. Before the construction of this clinic, affected Kenyans traveled for 2 hours to receive treatment in Nairobi and spent a significant portion of their income on travel expenses.

The clinic in the Muranga Hospital offers vials of clotting factor to stop acute bleeding. Medical professionals dispatch factor to the homes of patients who desperately need treatment. When the factor arrives, patients call the clinic and nurses teach the individuals how to properly inject themselves.

Since the clinic is located in a rural area with minimal education about blood disorders, the local community strongly believes that hemophilia comes from witchcraft. This false belief prevents affected individuals from seeking proper medical treatment. Health professionals from the clinic attempt to combat this myth by going out into the community and educating the public about hemophilia.

Save One Life

Save One Life came into existence in 2000 and aims to alleviate the financial burden of families in developing countries that hemophilia affects. More specifically, the organization helps patients by offering grants and emotional support.

Save One Life gives out grants of around $800 to low-income Kenyans with hemophilia to spend it on their small businesses. The grant helps patients to expand their business and earn extra money to pay for their medical treatments. Grants funded a range of businesses, from ridesharing services to dairy farming.

Also, the organization hosts gatherings for women with children that suffer from hemophilia. In a meeting of almost 50 women, they discussed their experiences dealing with the stigma of hemophilia and the difficulties of raising children without help from their husbands. The meetings allowed women to exchange advice and offer emotional support to each other.

With the help of nonprofit organizations and rural clinics, low-income individuals who experience hemophilia obtained medical treatments and lived more substantial lives. Raising awareness and educating the public about hemophilia in Kenya allows affected individuals to not feel ashamed about their diagnosis and to seek out proper medical care.

– Samantha Rodriguez-Silva
Photo: Flickr

Science Can Help End Global Poverty
Scientists around the world are passionate about making the world a better place. Almost 1 billion people around the world live in severe poverty. Such people lack access to food, clean water and sources of energy. They also lack much-needed medicine and access to healthcare. Advancements in science can help end global poverty.

Starvation and Diseases

Between 25,000 and 40,000 people die each day from causes such as starvation and diseases in impoverished countries, many of which are children. Each year, roughly 6 million children under the age of 5 die unnecessarily simply because they do not have access to clean water, doctors and food.

Science can help end global poverty by implementing more cost-effective strategies when it comes to advancements in testing for diseases. In developing countries, it can be difficult to conduct research for such testing. Chemist George Whiteside from Harvard University experimented with bubble wrap as a means for conducting blood tests. Whiteside found that he could create a sterile container from bubble wrap to test for anemia. More than 33% of the world’s population is anemic and this more affordable advancement could be useful in assisting the detection of the disease in developing countries. If the anemia undergoes detection, then those with it could receive treatment and lead more productive and healthy lives.

Agricultural Methods

Science can help end global poverty by enhancing agricultural methods. One particular issue affecting many developing countries is drought periods. Water conservation and distribution are barriers that science can address in developing countries that lack irrigation. The ratio of water necessary to grow a ton of wheat is 1,200:1 and the rice to water ratio is between 2,000-5,000:1. Satellite imagery can map out underground aquifers to monitor water supplies to help identify areas of the world that stand to benefit from increased water recycling programs.

How Innovations Have Helped End Global Poverty

While work is still necessary, there have been various successes attesting that science can help to this social plight. Malaria deaths reduced by 50% from 2000 to 2014 due to enhancements in testing. The availability of cell phones and wireless internet has assisted farmers with setting prices on their crops in Africa. Science has made advancements in helping developing countries grow healthier bio-fortified foods. Science has helped design stoves that burn cleaner and more available fuel made from animal byproducts. The utilization of these fuels also helps decrease respiratory infections. With proper governance and economic support, science can continue to help end global poverty and provide hope.

The U.S. Agency for International Development (USAID) began a project called the Global Development Lab in April 2014. Both governmental and non-governmental agencies along with universities began working collaboratively to end global poverty by 2030. Budgeted at $1 billion, USAID works to make progress in areas such as clean water, healthcare, ample and quality food security, schooling and energy accessibility.

Moving Forward So Science Can Help End Global Poverty

For science to make greater strides in assisting those living in extreme poverty policymakers in wealthy countries need to realize the importance of funding to make the necessary advancements. Scientists in the United States spend more than $20 billion per year working to improve biomedicine. To do this globally would be of a much greater cost and securing the support of policymakers pertaining to foreign aid budgets will be necessary to continue advancements.

–  Carolyn Lyrenmann
Photo: Flickr

The Wellcome Trust Fights Infectious Diseases
Amongst many others, three prevalent issues that continue to burden citizens across the world are mental health problems, weather changes and infectious diseases. Thankfully, organizations such as the Wellcome Trust specialize in these areas and hope to alleviate public health issues through research initiatives and partnerships. It incorporates work with businesses, academia, philanthropies, governments and the public to support the role science takes in solving health challenges. Not only does its work advance the study of science and medicine, but it also benefits under-developed countries needing assistance. Here is some information about the ways the Wellcome Trust fights infectious diseases around the world.

About the Wellcome Trust

The founder of the Wellcome Trust is Sir Henry Solomon Wellcome, a former philanthropist, and pharmacist who worked tirelessly to advance medical research. Born in 1853, Sir Henry Wellcome had an interest in pharmaceuticals and other cultures from an early age. After studying pharmacy and becoming a traveling pharmaceutical salesman, Wellcome formed Burroughs Wellcome & Co. in 1880 and worked to register a new form of tablets that were safer than traditional pills. He went on to profit handsomely from this company and used his wealth to fund many different scientific research laboratories, as well as collect different historical objects and books relating to medicine. Toward the end of his life, Sir Henry Wellcome formed the Wellcome Trust. This organization emerged to benefit those hoping to further biomedical research by providing funding. Today, the Wellcome Trust serves as the second-largest medical research charity in the world.

The Wellcome Trust strategizes to make improvements in public health by supporting various research programs. Wellcome works to advance research in the biomedical science sphere in hopes of bettering the understanding of health and disease. Its areas of scientific research include:

  • Genetics, Genomics and Molecular Biology
  • Infectious Disease and the Immune System
  • Cell and Developmental Biology
  • Physiology and Non-communicable Disease
  • Neuroscience and Mental Health

The Wellcome Fund’s Research Grants

The trust provides research grants to scientists, artists, educators and innovators in 70 countries. Many major collaborations have resulted from Wellcome-funded or co-funded research initiatives, such as the Cancer Genome Project and the Ebola Emergency Initiative. The trust provides funding schemes for potential grantees looking to increase research in biomedical science, population health, product development and applied research, humanities and social sciences, or public engagement and creative industries. In 2016, the Wellcome Trust received the title of the largest philanthropic funding of health research and others noted it for its people-focused funding.

The Wellcome Fund’s Initiatives in Africa and Asia

Wellcome’s work in Africa and Asia has resulted in significant impacts for those regions, such as recognizing treatments for infectious diseases and implementing programs that benefit African-led initiatives.

It has administered numerous programs in Africa and Asia, such as the KEMRI-Wellcome Trust Research Programme (KWTRP) in partnership with the Kenya Medical Research Institute, as well as The Africa Health Research Institute (AHRI). Both of these programs take a special interest in researching to understand the diseases that cause high mortality rates in their regions and use this information to improve public health in their area. The ability to understand the health of a population enables the use of intervention to improve the overall quality of life in that area. One significant impact that has resulted from this focus on Africa and Asia is the discovery of a more effective treatment for severe malaria, which went on to become the World Health Organization’s (WHO) global policy recommendation. Additionally, The Alliance for Accelerating Excellence in Science in Africa (AESA) emerged.

This organization fosters scientific excellence through mentoring upcoming research leaders and translating research into products and policies that improve the lives of people in Africa. With innovators in Africa leading it, the organization hopes to transform health research on the African continent to benefit citizens.

Distribution of Vaccines

The Wellcome Trust fights infectious diseases through the advancement of vaccines and helping distribute them to under-developed countries, which benefits impoverished citizens in more ways than one. About 2 million deaths each year are due to inadequate access to vaccines in low and middle-class countries. In impoverished countries that possess weak health care systems, easily preventable and treatment illnesses can run rampant and result in the death of children and already ill individuals. Many of these struggling nations also lack strong, well-established governments that can provide resources to help their citizens. This is why Wellcome supports the development of new and improved vaccines and hopes to enable vaccines that already exist for use in a broader context.

The Wellcome Trust understands that low and middle-income countries with high rates of infectious disease need to create their own immunization policies based on research evidence and prioritize cost-effectiveness. Therefore, it works with predominant organizations, such as Gavi, to fund and share relevant research with these areas to help them with their decision-making. Vaccines hold the potential to not only prevent sickness and death in impoverished nations but can also bolster education and economic development in struggling areas.

Ultimately, Wellcome uses its renowned research grant programs to cultivate discoveries involving global public health. Its initiatives reach across the entire world and result in new research that forces scientists to re-evaluate how to approach medicine and infectious diseases. Its discoveries also benefit struggling nations, such as areas in Africa and Asia, that greatly need invention to help their communities. The Wellcome Trust fights infectious diseases by helping the world gain a better understanding of science and supported some of the brightest minds in the scientific field to uncover improvements in public health.

– Hope Shourd
Photo: Flickr

Sickle Cell Anemia in Sub-Saharan AfricaThere are a total of 46 countries that compose sub-Saharan Africa. These countries account for 75% of the total cases of sickle cell anemia. Due to the high concentration of this disease in one area of the globe, high rates of early mortality have devastated sub-Saharan Africa. Researchers estimate that 50-90% of infants born with the disorder will die by the age of 5. In response, methodologies have been developed in hopes of eradicating sickle cell anemia in sub-Saharan Africa.

Early Screening

It is crucial to provide screening for newborns in order to diagnose children with sickle cell anemia as early as possible. Early detection of the disease is proven to increase survival rates. In under-resourced communities, many children have died without ever being diagnosed. Early detection allows for the initiation of treatments, therapies, physician follow-ups and medical attention. Previously, diagnoses of patients happened through isoelectric focusing and liquid chromatography, but they have shown to be inaccurate and expensive. Now, there are “point-of-care” diagnostic methods available that are affordable and provide accurate results.


A consequence of sickle cell disease (SCD) is an exponential increase in the transmission of bacterial infections. The main vaccination that has resulted in improvement for patients with sickle cell disease is penicillin prophylaxis. With the increased availability of penicillin and medical monitoring, mortality rates for patients with sickle cell anemia in sub-Saharan Africa will significantly decrease.

Treatment Therapies

Once diagnosed, there are numerous preventive and therapeutic measurements that can alleviate the symptoms of SCD. Data collected through years of research have proven that hydroxyurea is the most effective therapy for patients with SCD. In addition, proper hydration and nutritious supplements are key to curing non-critical patients. The most critical patients receive blood transfusions. Lastly, stem cell transplantations provide great improvements in SCD patients; however, its high cost often prevents utilization of this method.

Health Education

A simple method to increase the life expectancy of SCD patients is to provide accurate and useful information about the disease. Parents well-informed on this condition can properly identify symptoms their children display and can seek immediate medical attention. This leads to early detection so their child can receive necessary medications, therapies, vaccinations and treatments.

Global Advocacy

In recent years, more institutions have recognized the prevalence of sickle cell anemia in African and have shifted their focus to aiding those countries. The U.S. National Institutes of Health and the Gates Foundation created joint efforts in order to cultivate gene-based cures for both sickle cell disease and HIV.

The National Heart, Lung, and Blood Institute (NHLBI) and American Society of Hematology announced one of their priorities is to support the impoverished, disadvantaged countries across Africa in regard to sickle cell anemia. Also, the NHLBI Small Business Innovation research grant allowed for the utilization of the affordable, precise “point-of-care” diagnostic methods for SCD patients. Further advocacy for underprivileged, poor families is necessary to continue the fight in reducing sickle cell anemia in sub-Saharan Africa.

Despite its challenges, Africa has made major strides in improving sickle cell anemia in the last forty years. Continuing to utilize these methods would not only save vulnerable children, but their economy would flourish as well. A higher life expectancy has a direct correlation with an increase in projected lifetime incomes. This would result in more people contributing to their country’s economy and mobilizing their personal socioeconomic statuses. It is vital to take the above approaches to support patients with sickle cell anemia in sub-Saharan Africa.

Bolorzul Dorjsuren
Photo: Flickr