The Amazon rainforest offers amazing natural landscapes, but the dangers of diseases transmitted by tiny mosquitoes, like yellow fever, lie within them. Since early April 2025, Peru has seen an increase in yellow fever cases, mostly in vulnerable populations in the depths of the jungle and agricultural areas.

About Yellow Fever

Yellow fever is a disease transmitted by day-biting mosquitoes. It is considered a “High-threat disease” by the World Health Organization (WHO). Yellow fever does not have a specific antiviral drug to fight it once the virus is in the body. The best way to fight it is by preventing it with vaccination.

In early April, Peruvian authorities reported an outbreak of yellow fever cases in the regions of Amazonas, San Martín and Loreto. Yellow fever could reach a high 60% mortality rate in these regions because only a few people have been vaccinated in the past years.

The reach of vaccination campaigns shrank and vulnerable populations in less accessible areas like the jungle were affected. Twelve people died by the end of the month, all of them from vulnerable areas and without any records of previous vaccinations.

Effects on Vulnerable Populations in Peru

Mortality rates are higher among vulnerable populations, with 37 people already infected. Further, the U.S. Embassy in Peru and the Centers for Disease Control and Prevention (CDC) issued health alerts about the yellow fever outbreak, advising people to avoid areas affected by the disease. These warnings could result in reduced tourism, leading to a loss of income for many businesses that rely on it for their livelihood.

One of the biggest challenges preventing the disease is the logistical difficulty of distributing vaccines to remote areas. Vast distances and difficulty maintaining the cold chain in hard-to-reach regions significantly hinder vaccination coverage.

What Is the Government Doing?

The Peruvian government is trying to reactivate its vaccination campaigns, making resources available for people to find the closest vaccination centers. Peru’s Ministry of Health has announced a free vaccination campaign throughout the summer of 2025.

The Ministry of Health also sent 30,000 vaccines to the Amazon region in the past month, while volunteers are going town by town to vaccinate communities far from the few existing vaccination centers. However, Peru is not fighting the outbreak alone.

Since yellow fever also affects neighboring countries like Colombia and Ecuador, the Peruvian Ministry of Health joined forces in late April to launch a joint vaccination campaign along the border to prevent the disease from spreading between countries.

Final Remarks

Even though yellow fever has already claimed some lives in Peru, the government is taking action to prevent further spread and protect more people. Certain regions will inevitably face the consequences of this outbreak and the full economic impact, especially on families and businesses affected by the drop in tourism, remains uncertain until the epidemic is under control. 

– Luis Felipe Rios

Luis is based in New York, USA and focuses on Good News and Global Health for The Borgen Project.

Photo: Pxhere