Iran’s health system faces a complex mix of challenges. Chronic illnesses like heart disease, diabetes and high blood pressure are rising quickly, while infectious diseases such as tuberculosis, HIV and leishmaniasis still threaten vulnerable regions. These health issues are shaped not only by biology but also by environment, economy and access to care. Pollution, economic pressures and health care gaps make the picture even more complicated. From the air people breathe in Tehran to the food on their tables, these risks shape daily life and long-term well-being. Here is information about the diseases impacting Iran and the efforts in place to address them.

1. Non-Communicable Diseases (NCDs)

Chronic diseases, especially heart problems, are the most significant health concern. In 2019, cardiovascular diseases caused about 3.6 million disability-adjusted life years (DALYs) and nearly one-third of all deaths. By 2021, CVD was the second leading cause of death and disability, with 4,367 DALYs per 100,000 people.

The IraPEN program, part of a global initiative, targets prevention through primary care. After one year in pilot regions, results showed a reduction in 10-year CVD risk (from 0.198 to 0.177 in men, and 0.119 to 0.109 in women), lower average blood pressure, blood sugar and cholesterol, alongside a drop in smoking among men from 13.8% to 10.5%.

Still, lifestyle-related risks are rising. As of 2021, Iran had around 80 million NCD cases, with women carrying a slightly higher burden. Obesity, diabetes and hypertension are increasingly common. Experts stress raising awareness, healthier environments and stronger prevention programs to address diseases impacting Iran’s population.

Through community health centers and health houses, the program offers free screenings for blood sugar, blood pressure and cholesterol; provides early cancer detection (cervical, breast and colorectal); and includes health education and counseling on smoking cessation, healthy diet and physical activity.

2. Infectious Diseases

While many have been controlled, some persist:

• Tuberculosis and HIV: From 2018–2021, a study tracked 25,011 new TB cases, 2.68% also HIV-positive. People with both had longer treatments and lower success rates (65%) versus TB alone (83.4%).
• Leishmaniasis: Leishmaniasis still affects Esfahan, Khuzestan and Ilam provinces. Among military personnel, 2,894 cases were reported between 2018 and 2022. In southeast Iran, cases peaked in 2021 at 318, compared to 81 in 2018. Classified as a “neglected tropical disease,” it still causes suffering yearly.

Other infections such as HIV/AIDS, hepatitis, pneumonia, diarrheal diseases and zoonoses remain concerns in Iran and the wider region. These infectious diseases remain among the most persistent health challenges and diseases impacting Iran today.

3. Environmental Health Risks

Air pollution is one of Iran’s deadliest threats, blamed for around 40,000 premature deaths each year. In 2018, treatment costs and lost productivity from PM2.5 accounted for about 3.7% of GDP.

Despite the Clean Air Act (2017), smog still chokes major cities. In January 2025, the government announced plans to relocate the capital, citing Tehran’s deteriorating air quality. Pollution stands alongside infectious and chronic conditions as one of the key issues and health risks impacting Iran.

4. Access to Health Care

Iran faces a “double burden”: chronic disease and lingering infections. According to WHO’s Health at a Glance: Iran (2021), of 514,446 deaths that year, 57% were due to NCDs, 29% from communicable, maternal, perinatal and nutritional conditions. Medicine shortages and sanctions also undermine health care delivery, worsening the burden of diseases impacting Iran’s health care system.

Poverty significantly deepens Iran’s health challenges. Recent reports estimate that the poverty rate in Iran has hovered around 30% between 2019 and 2024—meaning approximately 25 to 26 million people live below the poverty line. Between 2011 and 2020, the share of Iranians living below the international poverty line rose from 20% to 28.1%. Many low-income households cannot afford nutritious food, safe housing or preventive care, increasing their risk of both chronic and infectious diseases.

5. Government Efforts

Iran has expanded IraPEN and, in 2014, formed the National Committee for NCD Prevention and Control to lead a nationwide response to chronic diseases. The committee, chaired by the Ministry of Health and supported by the Supreme Council for Health and Food Security, coordinates across multiple ministries to integrate NCD prevention into primary health care, promote tobacco control and expand early detection programs. It also monitors national progress toward WHO’s global targets, including reducing premature NCD deaths by 30% by 2030.

Looking Ahead

Chronic illnesses dominate, but infectious diseases and environmental hazards still claim lives and drain resources. Programs like IraPEN show promise, but real progress requires better health care, living conditions, education and infrastructure. Together, these factors illustrate the full scale of diseases impacting Iran and shaping its future.

– Katie Williams

Katie is based in the United Kingdom and focuses on Global Health for The Borgen Project.

Photo: Flickr