Pharmacovigilance Against Tuberculosis Infection
Every year, 30,000 individuals in Papua New Guinea are newly infected with tuberculosis. Tuberculosis is an airborne infection that causes the bacteria mycobacterium tuberculosis to develop into a disease that destroys organ tissue most commonly in the lungs. It can be fatal if left untreated. From those 30,000, one out of four are diagnosed; one out of five receive treatment; and less than half get successfully treated. If left untreated, one person can infect 10 to 15 people every year.
Increasing incidences due to minimal health care, poor housing and nutrition have contributed to poverty, overcrowding and people failing to complete their treatment. In fact only 50 percent of individuals have access to adequate healthcare. Children face the greatest risk of contracting disabling forms of tuberculosis. Unfortunately, 10 percent of children die from tuberculosis.
Papua New Guinea’s island of Daru has the highest rate of tuberculosis infection in the world. Out of 150,000 people on the island, 160 get infected with drug-resistant tuberculosis as of January 2016. The rise of two aggressive strains of tuberculosis are a result of recent developments of antibiotic resistance.
This resistance stems from multidrug resistant and extensively drug resistant tuberculosis. To treat tuberculosis infection, a daily regimen of injections, oral medication and supervised medical care of anywhere between six to 24 months is recommended.
With funding from the United States Agency for International Development and the National Department of Health, FHI360 is hosting a series training courses for doctors to introduce Bedaquiline. Janssen Pharmaceuticals developed Bedaquiline, the first new class of antibiotics approved by the United States Food and Drug Association in more than 40 years.
By utilizing pharmacovigilance—the science of early detection and adverse effects—Bedaquiline is slowly being introduced to practitioners and their patients. In fact, 85 courses of Bedaquiline have already been distributed to Daru hospital.
– Tiffany Santos
Photo: Flickr
