Poliovirus is a highly infectious viral disease that attacks the nervous system and could lead to paralysis or even death, mainly affecting children. Today, the virus mainly affects Afghanistan and Pakistan, along with other developing nations. The Global Polio Eradication Initiative (GPEI) is a partnership between the World Health Organization (WHO), Rotary International, U.S. Centers for Disease Control and Prevention (CDC), the United Nations Children’s Fund (UNICEF), the Gates Foundation and Gavi, the Vaccine Alliance that works to eradicate polio completely.

On December 8, 2025, it was announced that political leaders had collectively pledged $1.9 billion to the GPEI. In the fight against Polio, this generous fund has the potential to protect hundreds of millions of children from polio each year and possibly eradicate the virus.

How Polio Affects the World Today

Afghanistan and Pakistan remain the only countries where vaccines have not eliminated wild poliovirus. Other developing nations with low immunization rates continue to experience outbreaks of virus variants. This year, there have been 39 paralysis cases across Pakistan and Afghanistan.

Although polio cases are currently rare, “failure to stop polio in these last remaining areas could result in a global resurgence of the disease.” It is important to eradicate this virus in order to prevent it from spreading once again. Efforts have come very close to eradication and the recent GPEI funding will help bring the world even closer to this goal.

Successes in the Fight Against Polio

The GPEI was established in 1988 with the goal of ensuring that every child receives a polio vaccination. Since then, polio cases have dropped by 99% and vaccines have prevented approximately 20 million cases of paralysis. The virus once affected thousands of children across more than 100 countries but has now been eliminated in all except two, Afghanistan and Pakistan, where only a handful of cases occur each year.

About the Funds Against Polio

Pledges to the GPEI came from multiple donors, including:

• $1.2 billion from the Gates Foundation
• $450 million from Rotary International
• $140 million from the Mohamed bin Zayed Foundation for Humanity
• $100 million from Bloomberg Philanthropies
• $154 million from Pakistan
• $62 million from Germany
• $46 million from the United States
• $6 million from Japan
• $4 million from the Islamic Food and Nutrition Council of America (IFANCA)
• $3 million from Luxembourg

These funds will help protect 370 million children from polio through vaccination and reduce GPEI’s remaining resource gap. The shortage of vaccines and resources is a key reason polio still persists. With this recent funding, the complete eradication of poliovirus could become achievable.

– Renata Hirmiz

Renata is based in San Diego, CA, USA and focuses on Global Health for The Borgen Project.

Photo: Unsplash